The outbreak and rapid spread of SARS-CoV-2 Covid-19 has had a dramatic impact worldwide as the virus is highly contagious and spreads by air, from contaminated surfaces and via personal contact. Data suggests that the infection rate is higher than that measured for SARS, another virulent coronavirus. SARS-CoV-2 Covid-19 has rapidly spread in recent weeks to over 200 countries.
Social distancing is a primary strategy being used to slow the progress of transmission and infection, but this approach is not viable in the healthcare setting, where healthcare workers and sick patients are at constant risk and in close proximity to infected people. For the healthcare setting, a solution is needed that can kill the aerosolized virus and also kill the virus on surfaces, so that the spread of the disease can be slowed and the burden on the healthcare system eased.
HGI Industries Inc., a company based in Boynton Beach, Florida, has developed a novel, patent protected technology that can kill coronavirus Covid-19 in both the air and on surfaces. HGI manufactures a range of innovative sanitizing devices (Odorox® line) that are powered by high energy ultraviolet photochemistry, replicating the cleaning action of the sun. These devices kill 99.99% of viruses, bacteria, mold and other pathogens in air, on surfaces and on fabrics safely, in areas as small as an office or as large as hundreds of thousands of square feet. Odorox's proprietary technology sanitizes by generating effective levels of atmospheric hydroxyls, nature’s powerful atmospheric sanitizing oxidant that is both safe for occupied spaces and effective in sanitizing.
Airborne hydroxyls are the perfect sanitizing agent. They react with a broader range of chemicals and are over one million times faster than ozone, bleach and other sanitizing agents. They react so fast that they are consumed within a few seconds, so they never accumulate. Atmospheric hydroxyls are continuously produced by the action of the sun’s ultraviolet energy on oxygen and water in our atmosphere. They keep air safe to breathe by decomposing natural and man-made pollutants and killing microorganisms. They sanitize air and surfaces by a natural process called lysing, where the hydroxyls react chemically with the lipids, protein carbohydrates and other organic chemicals in the cell wall and membranes of viruses, bacteria and other pathogens. The interior contents of the cells leak and the organism is destroyed. The mechanism for killing microorganisms is not biological, so the bacteria or viruses cannot develop any form of immunity.
Odorox® kill rates across a broad range of microorganisms on hard and porous surfaces and in air are consistently over 99.9%. Kill rates for aerosolized microorganisms are exceptionally high in the measured range of 99.99% to 99.999% in two hours, as shown below from a study of the Odorox® MDU/Rx™ device presented to the FDA. This is particularly effective for the spread of viral disease as an important vector for transmission is inhalation of aerosolized virus.
Testing a new, virulent virus like the coronavirus Covid-19 is not easy for several reasons. Only major national labs like the Centers for Disease Control and Prevention (CDC) and National Institutes of Health (NIH) get samples soon after the emergence of a new virus. Most commercial labs are not equipped to test virulent virus as it requires biosafety containment facilities and protocols beyond their capability (level 3 or 4). A proven alternative approach adopted by the FDA is to test recognized surrogate viruses in studies where they are aerosolized to mimic the most important transmission mode. HGI conducted such studies to demonstrate the expected efficacy of its technology in killing and reducing the propagation of Coronavirus.
At the Aerosol Research & Engineering Laboratories (ARE Labs), a laboratory specializing in the study of aerosolized microorganisms, HGI conducted an FDA approved evaluation of the kill rates of two representative bacteria, two representative viruses and a mold as part of the approval process for its MDU/RX portable device. All five kill rates were between 4 and 5 log reductions (99.99% and 99.999%) within two hours, an exceptionally high, fast kill rate.
The FDA selected the MS2 and Phi-X174 viruses for this study because they had different viral sheaths and were representative of the two main types of viruses. MS2 bacteriophage (ATCC 15597-B1) is positive-sense, single-stranded RNA virus that infects the bacterium Escherichia coli and other members of the Enterobacteriaceae family. MS2 is routinely used as a simulant for pathogenic RNA viruses such as the coronavirus Covid-19 Phi-X174 (ATCC 13706-B1) bacteriophage i s a circular single stranded DNA based virus that infects the bacterium Escherichia coli. Phi-X174 was selected as a simulant for DNA based pathogenic viruses.”
The kill rate profiles for these viruses are shown below. It is notable that the baselines remain very stable during the trial and the rates of viral decline are similar and rapid, and achieve the FDA minimum level of efficacy of 99% (2 log reduction) within 15 to 30 minutes.
Odorox leveraged these and other safety and efficacy results to obtain FDA approval for its Odorox® MDU-Rx device (FDA 510k #133800 approval as a medical device). The MDU-Rx is approved by the FDA for use in occupied spaces in medical facilities.
Odorox's UV technology is unique: it is completely different from germicidal UV-C technology. Odorox devices generate more intense and high energy UV radiation within a patented reflection chamber. Different models are customized for specific applications and volumes of space to ensure that hydroxyl levels match the safe levels found in nature.
OdoroxAir portable devices can treat rooms from 300 to 6,000 square feet, either as standalone units or by integrating them into existing heating and ventilation ducts. Odorox commercial devices are designed to treat large spaces – hundreds of thousands of square feet - and feature integrated, interactive process controls and sensors that measure and control the levels of sanitizing oxidants ensuring consistent, safe levels.
OdoroxAir can design and implement custom solutions that effectively treat schools, colleges, commercial office spaces, healthcare facilities , fitness facilities which are at risk of corona virus Covid-19 contamination and propagation. OdoroxAir can help authorities to rapidly put in place solutions that sanitize the air and surfaces in almost anyfacily immediately with portable units and longer term, with permanent HVAC installations. OdoroxAir solutions can also be used to sanitize used previously used personal protective equipment and extend the the life of your critical supplies.
PARAMUS HIGH SCHOOL Steven Campbell Director of Buildings & Grounds Home of the Spartans
145 Spring Valley Road, Paramus, NJ 07652
(201) 261-7800 ext. 3017 FAX (201) 265-9483
Three years ago, we deployed the Pyure Odorox equipment throughout our district for mold remediation and for other related indoor air quality issues. The technology successfully resolved the matter and restored the IAQ results to a safe level. We then began using the equipment in the nurseÕs offices to reduce the cross contamination of the germs while students visited with noticeably affirmative results.
The Pyure Odorox equipment has also played a major role in our response to the pandemic; whether in the event of an exposure in a particular area of the buildings or as a non-chemical supplement to our enhanced cleaning and disinfection program.
I strongly recommend using the Pyure Odorox hydroxyl technology, as it has been a great addition to our arsenal as we effort to reduce the spread of the Covid 19 virus in our facilities. I canÕt thank Bio-Shine enough for bringing this technology to our district.
Steven Campbell Ð Director of Buildings & Grounds
Whilst writing, there has been a development since our telephone conversation that I would like to
share with you.
Sometime ago, I am assuming last week with all this heavy rain, my basement Cold Room/Storm Shelter had flooded out, it was full of contents and they had been sitting in water for some time. That coupled with the lack of air flow and humidity, caused everything to go moldy and there was visible mold on the floor, walls and ceilings.
We emptied this room of its contents and disposed of what was damaged beyond repair. We conducted
a cleanup and installed drying equipment and fans and once dried the mildew smell in this room was
So I took the initiative to use the loaner machine which Hydroxyl Environmental had provided our group. As previously mentioned I set the Boss Generator machine at high and added a couple of air fans to move the hydroxyls around the room. Within 2 days the mildew odor had completely been removed.
I personally am now totally sold on this product and its effectiveness in remediation and odor control.
I have copied our technical staff in on this email advising that my family and I were present throughout the use of this machine with no ill effects.
So to summarize, many thanks for the use of this machine, I am happy to share its success with our
many branches across Canada and help to recommend your product. There is no doubt it looks like
Hydroxyl generators and their effectiveness are the way forward.
Once again many thanks.
Major National Canadian Restoration Firm
Canadian Restoration Firm
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Odorox hydroxyl technology destroys 99.9% of germs, bacteria, mold, mildew, voc's and viruses in the air and on porous and non-porous surfaces which can cause illness and infections. MDU/RX FDA approved and safe to use in spaces occupied by people, pets, and plants.